For Current Projects, please visit the Lab Website
Past Projects:
Medical Diagnostics
Biosensors Lab developed handheld, field-ready or point-of-care PCR and LAMP devices for analyzing nucleic acids from myriads of human, animal, food, and environmental samples. Smartphone (or Arduino/Raspberry Pi with CMOS camera) is being used as an optical sensing device as well as data processing/storage device. Unlike the other real-time quantification methods for PCR and LAMP, we are the first in utilizing interfacial effects to drastically reduce the analysis time and improve the sensitivity.
Objective: Smartphone biosensors for medical diagnostics
Researchers: Robin Sweeney, Cayla Baynes, Vina Nguyen, Benjamin Alouidor, Elizabeth Budiman, Jacob Pfeiffer
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1. Smartphone attachment for quantifying the band intensities from lateral flow assays. 2. Smartphone-based fluorescence microscope. 3. Paper microfluidics for quantifying bacteria. 4-5. Smartphone application for quantifying the optical signals from paper microfluidics. |
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Handheld PCR and LAMP
Objective: Handheld PCR and LAMP systems utilizing interfacial tension for pathogen identification.
Researchers: Ariana Nicolini, Tiffany Ulep, Alexander Day, Samuel Kim
Collaborator: Prof. David Galbraith (U Arizona)
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1. DOTS qPCR device. 2. DOTS qPCR with smartphone monitoring of interfacial tension. 3. Interfacial effects enable low theshold cycle detection and inhibition relief. |
Tissue Engineering and Organ-on-a-Chip
Objective: Use of nanostructured surfaces for tissue engineering and organ-on-a-chip applications.
Researchers: Soohee Cho, Kattika Kaarj, Soo Chung, Jennifer Ngo, Ryan Zenhausern
Collaborators: Prof. Terrence Monks (Wayne State U)
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1-2. Nanostructured ensemble surfaces on e-beam nanopatterns and electrospun nanofibers. 3. Organ-on-a-chip system. 4. In situ GGT monitoring on organ-on-a-chip. |
Water Quality and Food Safety
Objective: Lab-on-a-chip for water quality and food safety.
Researchers: Katherine McCracken, Soohee Cho, Soo Chung, Trinny Tat, Veronica Paz, Lane Breshears
Collaborator: Prof. Kelly Reynolds (U Arizona)
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1. E. coli detection from lettuce. 2. Salmonella detection from poultry packaging. 3. Monitoring bacterial contamination from soil with lab-on-a-chip. 4. Monitoring microbial contamination on ground beef with smartphone. 5. Wine tasting on paper microfluidics. |